A study published in 2024 by the BMJ medical journal found that exercises such as walking, jogging, yoga and strength training were more effective at alleviating depression than other exercises, especially when the activity is intense. In fact, the positive effects of some forms of exercise were comparable to the positive effects of therapy and medication.
“Our findings suggest that practitioners could advocate for most patients to engage in exercise. … Those who are able may want to choose more intense exercise in a structured environment to further decrease depression symptoms,” says the study.
The study identifies the following kinds of exercise as contributing significantly or moderately to the reduction of depression symptoms:
The study says walking, jogging, yoga and strength training were more effective than other exercises.
“Although walking or jogging were effective for both men and women, strength training was more effective for women, and yoga or qigong was more effective for men,” the researchers wrote. “Yoga was somewhat more effective among older adults, and strength training was more effective among younger people.”
Dance appears to be a promising treatment for depression, the study says, but research limitations kept the study’s authors from more forcefully recommending dance.In some cases, “clinically meaningful effects” arose when exercise was combined with aerobic exercise of SSRIs (selective serotonin reuptake inhibitors, a commonly prescribed group of antidepressants), the study says.
The study pulled data from 218 studies encompassing 14,170 participants.
Jarrow Formulas SAMe 200 Description
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Mood Support
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Regular Strength
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Naturally Derived
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S-Adenosyl Methionine Active S, S Form
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200 mg (net yield) SAMe from 400 mg SAMe Tosylate Disulfate
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Supports Balanced Mood, Joint Health, and Liver Function
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In Foil Blister Pack
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Enteroguard® Coating
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Gluten Free
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Vegan
Jarrow Formulas® SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
With More of the Biologically Active S,S than R,S Form
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made by microbiological fermentation and then processed without chemical solvents to preserve 68-80% (S,S) SAMe.
SAMe supports:
• Brain Metabolism and Mood
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes. It has also been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood.
• Joint Health
SAMe supports the production of healthy connective tissue through transulfuration. In this transsulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.
• Liver Function
SAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.
Jarrow Formulas® SAMe 200 is foil blister-packed to maximize stability and provides 200 mg S-Adenosyl Methionine derived from 400 mg of SAMe Tosylate Disulfate.
Suggested Use: Adults take 1 tablet 1-2 times a day on an empty stomach or as directed by your qualified healthcare professional.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
| Amount Per Serving | % Daily Value | |
| S-Adenosyl Methionine (from 400 mg of SAMe Tosylate Disulfate) | 200 mg | * |
Do not use if pregnant or nursing. Individuals with Parkinson’s disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use.
