Life Extension Benfotiamine with Thiamine Description
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The body needs vitamin B1 (thiamine) to support healthy blood sugar metabolism, but it doesn’t make B1.
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This formula delivers fat-soluble benfotiamine and water-soluble thiamine to support already-healthy levels of vitamin B1, maintain blood sugar levels already within normal range, promote brain and cardiovascular health, and help inhibit glycation and protect from oxidative stress.
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It contains 120 vegetarian capsules, enough for a 1-month supply.
Benfotiamine is a fat-soluble form of vitamin B1 (thiamine). Thiamine is needed for normal blood sugar metabolism via a non-oxygen-dependent metabolic pathway called the pentose phosphate pathway. The products of this pathway are needed for fatty acid, amino acid and nucleotide synthesis. Adequate levels of thiamine are especially critical to supporting healthy brain function, where cells rely on the pentose phosphate pathway for energy.Thiamine also helps encourage the body’s tissues against advanced glycation end products and oxidative stress, making maintaining optimal levels important for supporting cardiovascular and metabolic health.
Unfortunately, thiamine in most supplements (thiamine hydrochloride) is water-soluble, which makes it less available to the interior of the cell. As a fat-soluble form of thiamine, benfotiamine can easily penetrate the inside of cells. It has been shown to support thiamine levels faster and for longer than the water-soluble thiamine.
Thiamine is a cofactor for the pentose phosphate pathway enzyme, transketolase.In one study, benfotiamine effectively increased transketolase activity in cell cultures by 300%, compared with 20% for thiamine. This activation helps promote blood vessel health.Benfotiamine also supports a healthy inflammatory response in nuclear factor-kappa B (NF-kB) and encourages expression of nuclear factor erythroid 2-related factor 2 (Nrf2), which supports antioxidant activity in cells.
Benfotiamine has further been found to inhibit formation of neurofibrillary tangles and tau protein damage in brain tissue and support healthy lifespan in preclinical studies, as well as maintain endothelial cell function.
Overall, benfotiamine can support healthy glucose metabolism and promote healthy blood glucose levels in those already within normal range. Benfotiamine with Thiamine is a dietary supplement that can help maintain blood sugar levels in those already within normal range and support the health of the nerves, kidneys, eyes, blood vessels and heart.
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Sugar metabolism – Your body needs vitamin B1 to metabolize glucose, or blood sugar, but the body doesn’t make vitamin B1 on its own. Our formula delivers a fat-soluble form of B1 to support healthy blood sugar metabolism.
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Bioavailable vitamin B1 – Thiamine is vitamin B1. Benfotiamine is a fat-soluble form of vitamin B1, which makes it more bioavailable. Benfotiamine has been shown to support thiamine levels faster and longer than thiamine.
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Brain and heart health – Healthy thiamine levels help inhibit glycation and oxidative stress. B1 also helps maintain brain and cardiovascular health. Benfotiamine helps maintain endothelial health and function, the delicate inner lining of blood vessels.
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Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.?
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Live your healthiest life - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. That’s why so many of our nutritional formulas are designed using specific ingredients and amounts based on scientific studies.
Take one (1) capsule four times daily, or as recommended by a healthcare practitioner.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
| Amount Per Serving | % Daily Value | |
| Thiamine (vitamin B1) (as thiamine HCI) | 25 mg | 1667% |
| Benfotiamine | 100 mg | * |
Do not exceed recommended dose. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant of lactating.
